Endocrine Abstracts

Introduction: The autoimmune polyglandular syndrome (APS) is characterised by the coexistence of at least two glandular autoimmune mediated diseases. We report a combination of an autoimmune thyroid disease, Addison’s disease and an atypical involvement of the parathyroid gland.Case report: A 73-year-old white woman was admitted to our clinic for evaluation due to recurrent syncopes during last 3 years, along with vertigo, cold sweats, and general f...

Introduction and aim: Cytokines play a crucial role in modulating immune response in both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). They may contribute to drive the autoimmune response skewing toward the Th17 phenotype and away from Th1 or Th2 phenotypes. Recent studies revealed an essential role of Th17 cells and their cytokines in the development of autoimmune thyroid diseases (AITD). However, participation of Th17 cells in the pathogenesis of GD is ...

Introduction: Pregnant women are at risk for selenium deficiency, which is known to maintain adequate function of immune system and thyroprotective enzymes. Same, iodine is an essential micronutrient for thyroid hormone synthesis and important endocrine regulator of early brain development. Our previous study revealed that 81% of pregnant women in Latvia have insufficient levels of iodine. The aim of the present study was to evaluate iodine and selenium supply during pregnancy...